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Monday, 5:10 AM

October 7, 2025

Good morning news friend! Discover today’s defining stories and the future they set in motion. 📰🌟

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Trump Opens Door to Health Care Talks

President Trump expressed willingness to negotiate with Democrats on health care subsidies to end the government shutdown that began October 1.

The shutdown continues amid Democratic demands to extend Affordable Care Act subsidies and Medicaid funding, while Republicans demand reopening the government first.

Failure to renew ACA subsidies by year-end could raise premiums for millions. Hundreds of thousands of federal workers remain furloughed or unpaid, with payroll disruptions expected by mid-October, potentially dampening consumer spending and growth. Federal food aid programs face funding shortages.

Amid shutdown chaos, the General Services Administration quietly rehired nearly 75% of its laid-off employees, keeping crucial federal buildings operational despite looming funding shortages.

Sources: Bloomberg, WallStreetJournal, NYTimes, AP News, Federalnewsnetwork.

OpenAI Ignites AI Chip Race

OpenAI partnered with AMD to buy hundreds of thousands of AI chips delivering 6 gigawatts of compute power starting in H2 2026.

OpenAI can acquire up to 160 million AMD shares (~10% stake) at $0.01 each, contingent on milestones and AMD stock reaching $600. AMD shares surged 34% on the deal.

AMD expects $100 billion+ revenue over four years from AI demand, competing with Nvidia, which holds 75% AI GPU market share and has a $100 billion OpenAI chip deal for 10 gigawatts. OpenAI’s valuation is $500 billion with $4.3 billion H1 2025 revenue. Partnerships with Spotify, Zillow, and Mattel signal an enterprise focus amid growing AI inference workloads.

OpenAI’s deal with AMD isn’t just about chips—it includes an option to buy a 10% stake in AMD, potentially giving OpenAI influence over AMD’s corporate strategy if key stock milestones are hit. Read the full deal here.

Sources: Bloomberg, AP News, Reuters, Reuters, WallStreetJournal.

Paramount Acquires The Free Press

Paramount Skydance acquired Bari Weiss’s The Free Press for about $150 million. Weiss, founder of the outlet known for challenging mainstream narratives, was named CBS News editor-in-chief, reporting to Paramount CEO David Ellison.

The Free Press, with 1.5 million subscribers, will remain independent under Paramount. Ellison aims to revitalize CBS News, currently third in broadcast ratings, by appealing to politically moderate audiences. Weiss plans new debate-style shows and newsroom engagement to build trust.

This follows CBS executive departures amid political coverage tensions and a $16 million 2024 Trump lawsuit settlement. The deal aligns with Paramount’s strategy to modernize CBS through a multiplatform digital model targeting center-left to center-right viewers.

Despite overlooking traditional editorial hierarchy, Bari Weiss reports directly to Paramount CEO David Ellison, signaling a radical power shift inside CBS News—find out how this could reshape the network’s future.

Sources: AP News, Reuters, AXIOS, Pbs, WallStreetJournal.

Trump Pushes Fannie Mae and Freddie Mac IPO

President Trump urged Fannie Mae and Freddie Mac to boost homebuilding, citing 2 million empty lots. Both firms plan to close New York offices amid a probe by Attorney General Letitia James.

Their IPOs could value the companies near $500 billion, aiming to raise $30 billion, potentially the largest ever. Major banks including Goldman Sachs, Citigroup, and JPMorgan Chase compete to lead the deal. Internal tensions between Treasury and FHFA officials may delay the IPO, originally expected this year.

The firms remain under federal conservatorship since 2008, with the government owning about 80% of common stock. Bankers seek investor protections to stabilize the mortgage market.

One bank reportedly proposed a valuation below $500 billion, sparking tension within the Trump administration as officials clash over the IPO’s price and structure—read more to see how it could reshape the deal.

Sources: Economictimes, WallStreetJournal, Housingwire.

Immune Protein Punches Holes in Heart

Massachusetts General Hospital researchers identified a protein, Resistin-like molecule gamma (RELMy), released by neutrophils after heart attacks.

RELMy damages heart muscle cells by creating membrane holes, disrupting electrical signals and causing ventricular tachycardia (VT) and ventricular fibrillation (VF). These arrhythmias frequently occur within 48 hours post-heart attack. Mice lacking the RELMy gene showed a 12-fold reduction in arrhythmias.

Human heart tissues from heart attack patients exhibited elevated levels of a similar protein, Resistin. The findings suggest targeting RELMy could reduce deadly heart rhythms. Researchers plan to develop RELMy-blocking drugs, with preclinical and clinical trials to follow, potentially improving survival after heart attacks.

The study reveals that resistin-like molecule gamma actually pierces heart muscle cell membranes, creating pores that disrupt electrical signals—an immune “misfire” that’s a new target for preventing sudden cardiac death. Read more.

Sources: SciTechDaily, Technologynetworks, News-Medical, Medicalxpress.

Revealing Parkinson’s Hidden Trigger

Researchers developed ASA-PD, an ultra-sensitive imaging method that directly visualizes alpha-synuclein oligomers—protein clusters believed to trigger Parkinson’s disease—in post-mortem human brains.

Examining tissue from 15 Parkinson’s patients and 15 controls, they detected 1.2 million oligomers, finding larger, more numerous clusters and a unique oligomer subclass present only in Parkinson’s brains. These oligomers appear years before symptoms, suggesting potential early biomarkers. Parkinson’s affects 166,000 people in the UK, with global cases projected to reach 25 million by 2050.

The breakthrough offers new avenues for early diagnosis and targeted treatments, and may aid understanding of other neurodegenerative diseases like Alzheimer’s and Huntington’s.

The ASA-PD technique not only visualizes millions of oligomers but also pinpoints their exact locations, potentially enabling targeted therapies to specific brain cell types—read how this reshapes Parkinson’s treatment.

Sources: SciTechDaily, Ac, Openaccessgovernment, Technologynetworks.

“The secret to a long life is mostly a matter of not being a fool or a scoundrel, for you will find that vice is a mighty efficient undertaker. A man who lives what they call a "fast life" is really just in a powerful hurry to get to his own funeral; he burns his candle at both ends and calls the bright sputtering a good time.”

Did you know we also write in-depth deep dives? They are long, packed with insights, and have received rave reviews. If you’re up for a detailed, action-packed read, check them out:

• The Retirement Tax Bomb

• The Gut Brain Axis

• The Healthcare Hammer

• The Resilient Retirement

• Inflammation Crisis

• AI Proof Professionals

Baked with love,

Anna Eisenberg ❤️