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Monday, 5:23 AM

November 1, 2025

Good morning news friend! Discover today’s defining stories and the future they set in motion. 📰🌟

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Trump Threatens Military Action in Nigeria

President Trump threatened military intervention in Nigeria over alleged mass killings of Christians by Islamist militants, instructing the Pentagon to prepare plans for possible action.

He warned the US might cut all aid and invade if Nigeria does not stop the violence. Nigeria’s government denies religious intolerance, citing efforts to protect all faiths amid ongoing conflicts involving Boko Haram and ISIS West Africa, which have killed over 40,000 and displaced 2 million since 2009.

Analysts note most victims are Muslim, with violence also driven by Muslim-Christian herder-farmer clashes. US Defense Secretary supports preparation for action. Nigeria seeks US cooperation but warns against violations of its sovereignty.

Sources: AP News, France24, BBC, Reuters, Reuters. 

Train Mass Stabbing in London

A stabbing attack on a Doncaster-to-London train injured 11 passengers, nine critically. The train stopped at Huntingdon, where police arrested two British men, releasing one without charge.

Authorities ruled out terrorism as a motive. A rail staff member who confronted the attacker remains in life-threatening condition but is credited with saving lives. Emergency responders arrived promptly, with two victims still in critical care at Addenbrooke’s Hospital.

The train driver’s swift actions aided rescue efforts. Transport Secretary Heidi Alexander pledged increased police presence on trains. Huntingdon station remains closed during investigations, highlighting vulnerabilities in UK rail security and the importance of rapid emergency response.

Sources: AP News, BBC, EuroNews, Reuters.

OPEC+ Halts Oil Output Growth

OPEC+ will increase oil output by 137,000 bpd in December 2025 but pause growth from January to March 2026 due to concerns over a looming supply surplus.

Since April, production targets rose over 2.7 million bpd but growth slowed amid fears of stock builds early next year. Saudi Arabia cited typical first-quarter demand drops as a reason for the pause. Analysts expect global supply could exceed demand by nearly 4 million bpd in 2026.

Western sanctions on Russian oil firms and U.S.-Venezuela tensions add uncertainty. Oil prices rose from $60 to $65 per barrel amid sanctions and U.S. trade optimism. OPEC+ will monitor markets and holds about 2 million bpd in cuts through 2026.

Sources: Reuters, Bloomberg, NYTimes, Scmp.

Did you know we also write in-depth deep dives? They are long, packed with insights, and have received rave reviews. If you’re up for a detailed, action-packed read, check them out:

• 2026 tax Sunset

• The Widowhood Penalty

• The Asset Protection Blueprint

• The Retirement Tax Bomb

• Inflammation Crisis

• The Gut Brain Axis

The End of Labor Hoarding

Corporate America is ending its pandemic-era hiring freeze as major firms like Amazon, UPS, Target, and Meta announce tens of thousands of layoffs.

Amazon, with 1.5 million employees, cut 14,000 jobs; UPS eliminated 48,000 positions; Target plans 1,800 corporate cuts. Layoffs reflect shifts toward leaner workforces amid rising AI adoption, tariffs, weaker demand, and economic uncertainty.

The US unemployment rate rose from 3.4% in April 2023 to 4.3% in August 2025, with job growth slowing to 22,000 in August 2025. Investors responded positively to cost-cutting announcements.

Companies expect AI to automate tasks, allowing further payroll reductions. Layoffs threaten a volatile labor market, impacting recent graduates and job seekers.

Sources: WallStreetJournal, Msn, Investing.

Chromosome Stability and Disease

Researchers identified that replication protein A (RPA) stimulates telomerase to maintain telomeres, preventing diseases like aplastic anemia, myelodysplastic syndrome, and acute myeloid leukemia.

Using AI (AlphaFold), they explained telomere-related diseases lacking direct telomerase mutations by linking them to disrupted RPA function. Separately, Rtt105 was found to chaperone RPA in yeast, promoting its nuclear import via Kap95 and enhancing RPA binding at DNA replication forks.

Without Rtt105, DNA replication slows by 5-10 minutes under stress, raising genome instability. These findings clarify protein roles in genome stability and telomere maintenance, offering new diagnostic targets and potential treatment strategies for cancers and bone marrow disorders tied to replication stress and telomere dysfunction.

Sources: SciTechDaily, Bioengineer, Embopress.

Halting Dry Macular Degeneration

Aalto University researchers developed a laser therapy using mild near-infrared heat to activate protective cellular responses in retinal tissue, targeting dry age-related macular degeneration (AMD), which affects 20 million U.S. adults 40+.

The treatment boosts heat shock proteins and autophagy to repair and clear damaged proteins without harmful overheating. Successful tests in mice and pigs pave the way for human safety trials in Finland starting spring 2026.

Researchers founded start-up Maculaser to commercialize the therapy, aiming for availability within three years. This approach could be the first to halt dry AMD progression, potentially preserving central vision for millions.

Sources: SciTechDaily, EurekAlert.

“A noble soul knows that every man is bound to stumble, and is more interested in finding an excuse for the fall than in measuring the size of the mud puddle.”

Baked with love,

Anna Eisenberg ❤️