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Anna's Daybreak News

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Tuesday, 5:23 AM

November 25, 2025

Good morning news friend! Discover today’s defining stories and the future they set in motion. 📰🌟

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Witkoff Advised Russia

On October 14, Trump envoy Steve Witkoff advised Putin’s aide Yuri Ushakov on framing a 28-point Ukraine peace plan, urging Putin to praise Trump for the Gaza ceasefire and call him before Zelensky’s White House visit.

The plan calls for Ukraine to cede Donbas, drastically reduce its military, and renounce NATO membership. Zelensky is open to U.S. proposals but has reservations. Trump praised Witkoff’s approach as standard negotiation.

Witkoff will visit Moscow soon, possibly with Jared Kushner, to advance talks. Trump delayed his initial Thanksgiving peace deadline, awaiting a final deal. European leaders remain skeptical amid ongoing Russian strikes.

Republican Representative Don Bacon criticized the envoy’s approach, accusing him of favoring Russian interests and calling for his dismissal. The Kremlin condemned the leaked call as undermining negotiations.

Sources: Bloomberg, AP News, AP News, Bloomberg, France24, Reuters.

Challenging Auto Safety Rules

In January 2026, the Senate Commerce Committee will hold a hearing to challenge auto-safety rules requiring technologies like automatic emergency braking and child reminder alarms.

Senate Republicans argue these mandates increase vehicle costs—average new car price rose to $50,000 from $38,000 pre-pandemic—without significantly reducing accidents. Automakers, including Detroit’s Big Three and Tesla, are summoned to explain price hikes.

Republicans claim major safety gains occurred decades ago and seek to delay the 2029 automatic braking mandate, citing potential collision risks. Safety advocates insist mandates save lives amid 40,000 annual road deaths.

The hearing will also address how clean-air and fuel-economy rules contribute to higher costs and affect electric vehicle adoption.

Sources: WallStreetJournal, Investing, Tipranks. 

Medicare Slashes Prices on 15 Top Drugs

Medicare will cut prices on 15 top drugs starting in 2027, saving about $12 billion and reducing patient costs by $685 million.

Key cuts include Novo Nordisk’s Ozempic and Wegovy, from $959 to $274 per 30-day supply, Pfizer’s Ibrance halved to $7,871, and reductions on drugs for cancer, asthma, lung disease, and IBS. These drugs accounted for $42.5 billion in 2024 Part D spending among 5.3 million beneficiaries.

Discounts average 36%, up from 22% in 2024. The price negotiations stem from the Inflation Reduction Act of 2022, targeting more drugs through 2029. Some prices remain higher than those in other wealthy countries despite cuts.

Sources: Bloomberg, Usatoday, WallStreetJournal, Reuters, Reuters.

Did you know we also write in-depth deep dives? They are long, packed with insights, and have received rave reviews. If you’re up for a detailed, action-packed read, check them out:

• Modern Inheritance Playbook

• Mastering Executive Metabolism

• Muscle-Centric Medicine

• 2026 tax Sunset

• The Widowhood Penalty

• The Asset Protection Blueprint

• The Retirement Tax Bomb

• Inflammation Crisis

• The Gut Brain Axis

Economy Shows Mixed Signals

September 2025 retail sales rose 0.2% month-over-month, below expectations, with declines in clothing, electronics, and online shopping offset by food services (+0.7%) and nonstore retailers (+6.0% year-over-year).

Consumer confidence dropped to 88.7 amid a 4.4% unemployment rate, the highest in four years. Producer Price Index increased 0.3% month-over-month and 2.7% year-over-year, led by energy (+3.5%) and food (+1.1%).

October’s budget deficit hit $284 billion, up 10% year-over-year, driven by early benefit payments; adjusted deficit improved 29%. Tax receipts rose 24%, with customs duties reaching a record $31.4 billion.

The Fed cut rates 25 basis points in October and is expected to pause in December. The S&P 500 gained 0.91%.

Sources: Census, Dailyforex, Reuters, Reuters.

Obesity Linked to Early Brain Damage

Obesity in adults aged 20-30 is linked to early brain damage, shown by higher inflammation and liver stress markers, and elevated neurofilament light chain (NfL), a neuron damage protein.

Low blood choline, essential for liver and brain health, correlated with higher NfL and linked to insulin resistance and metabolic dysfunction. Women had lower choline than men, relevant given their higher Alzheimer’s risk. Weight-loss drugs like GLP-1 therapies may reduce calorie and choline intake, potentially harming metabolic and brain health.

Many young Americans do not meet recommended choline levels. Researchers urge more study on early metabolic stress and nutrient supplementation to protect neurons and support brain aging.

Sources: SciTechDaily.

Your Brain’s State Shapes What You See

MIT researchers found that two prefrontal cortex areas—anterior cingulate area (ACA) and orbitofrontal cortex (ORB)—differently modulate visual perception based on arousal and movement.

ACA sharpens visual detail as arousal rises, enhancing weak or uncertain stimuli, mainly connecting with layer 6 neurons in the primary visual cortex (VISp). ORB activates only at very high arousal, reducing visual detail to filter distractions, targeting layer 5 neurons.

Both areas send movement-related signals to the primary motor cortex (MOp) but differ in VISp signaling. Blocking their inputs confirmed distinct effects on visual encoding.

These findings suggest prefrontal subregions selectively influence brain areas, dynamically shaping sensory processing.

Sources: SciTechDaily.

“You can generally bet that a man who keeps a laundry list of his neighbor's sins is trying to hide a heap of dirty linen of his own. He figures if he paints the other fellow black enough, he might look white by comparison, which is the logic of a fool.”

Baked with love,

Anna Eisenberg ❤️